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The increased loading dose can be repeated as many times as required, titrated against the patient's pain level and the side effects of the opioid.Patient weight is a useful guide in initiating PCA dosing, even though the correlation between analgesic requirement and weight is poor.

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You will be reimbursed network pharmacy rates, less co-pays.

Patient-controlled analgesia (PCA) is a method of providing analgesia using a computerized pump that allows patients to self-administer predetermined doses of opioids.

The delivery of small, frequent intravenous boluses of opioids results in reasonably constant serum concentrations of the opioid.

Since there is marked inter-patient variability in the amount of analgesic required for pain relief, the loading dose must be titrated to effect.

Many studies have demonstrated a five fold variability in the quantity of intravenous opioid required to produce equivalent analgesia after surgery.


  1. Apr 3, 2017. Zyrtec and Claritin are similar over-the-counter allergy medicines. Your choice. Antihistamines like Zyrtec and Claritin are designed to calm the histamine reaction your body has when it's exposed to an allergen. Taking them at the same time that you take sedating drugs can make you extremely sleepy.

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